Scottish Cup
| Final | |||
| Friday 13th May 2022 | |||
| St Cadocs YC | 1 | Kilwinning Rangers FC 0 | |
| Semi Final | |||
| 6th March 2022 | |||
| St Cadocs YC | 3 | Auchinleck Talbot | 1 |
| 4th Round | |||||
| 15th/16th January 2022 | |||||
| Referee | |||||
| Irvine Victoria Thistle | 3 | Knightswood FC | 5 | Jim Pearson | |
| East Craigie Swifts | 0 | Langcraigs FC Blues | 6 | ||
| 5th Round | |||||
| 22nd/23rd January 2022 | |||||
| Referee | |||||
| Linwood Rangers YC | 0 | St Cadocs YC | 6 | David Dow | |
| Auchinleck Talbot | 9 | Langcraigs FC Blues | 2 |
| 4th Round | |||
| 11th/12th December 2021 | |||
| East Craigie Swifts | P | Langcraigs FC Blues | |
| Broxburn Athletic Colts Diamonds | 1 | St Cadocs YC | 3 |
| Irvine Victoria Thistle | P | Knightswood FC | |
| Linlithgow Rose CSC | 3 | Linwood Rangers YC | 5 |
| 20th/21st November 2021 | |||||
| 3rd Round | |||||
| Referee | |||||
| Drumchapel Amateurs | 3 | Clydebank FC | 2 | ||
| Pollok United | 3 | Irvine Victoria Thistle | 4 | Stuart McLearie | |
| Linwood Rangers YC | v | Vale of Leven | |||
| Vale of Leven unable to field a team | |||||
| Langcraigs FC Blues | 7 | Cambuslang FC | 4 | Jim Pearson | |
| Port Glasgow BC Orange | 3 | Knightswood FC | 3 | Alistair Barclay | |
| Knightswood won 7-6 on penalties | |||||
| St Cadocs YC | bye | ||||
| 6th/7th November 2021 | |||||
| 2nd Round | |||||
| Referee | |||||
| Linwood Rangers YC | 6 | Harmony Row YC | 1 | Stuart McLearie | |
| Pollok United | 8 | Hillwood FC Whites | 2 | Danny Boyle | |
| Milngavie FC | 1 | Drumchapel Amateurs | 4 | David Cameron | |
| Langcraigs FC Blues | 5 | Busby AFC | 1 | Jim Pearson | |
| Erskine YFC | 1 | Knightswood FC | 3 | Alistair Barclay | |
| St Cadocs YC | 16 | Erskine YFC Reds | 0 | Tommy Wilson | |
| Castlemilk Boys Club | 0 | Irvine Victoria Thistle | 3 | ||
| Holytown Colts FC | 0 | Clydebank FC | 2 | ||
| Glasgow Red Star Athletic | 0 | Port Glasgow BC Orange | 3 | ||
| East Kilbride Burgh United | 0 | Cambuslang FC | 5 | ||
| Vale of Leven | bye |
| 2nd/3rd October 2021 | |||||
| 1st Round | |||||
| Referee | |||||
| Milngavie FC | 7 | Clyde FC Community | 0 | Stuart McLearie | |
| Stamperland FC | 3 | Harmony Row YC | 4 | David Cameron | |
| Langcraigs FC Blues | 9 | East Ren FC | 1 | Danny Lafferty | |
| St Cadocs YC | 4 | West End Soccer Glasgow | 0 | Gerry Lyons | |
| Erskine YFC | 4 | St Cadocs YC United | 1 | Kenny Diver | |
| Pollok United | 3 | Barrhead YFC | 1 | Jim Pearson | |
| Linwood Rangers YC | 2 | Thorn Athletic YFC | 0 | Andy Robertson | |
| East Kilbride Burgh United | 3 | Dumbarton United | 2 | ||
| Drumchapel Amateurs | 6 | Summerston YFC | 1 | ||
| St. Patrick's Sports Academy | 2 | Cambuslang FC | 4 | ||
| Holytown Colts FC | 6 | Ardencaple FC | 0 | ||
| Vale of Leven | 3 | Giffnock North BC Athletic | 0 | ||
| Erskine YFC Reds | 3 | Helensburgh FC (folded) | 0 | ||
| Port Glasgow BC Orange | 3 | Ferguslie Star Youth (folded) | 0 | ||
| Clydebank FC | 3 | Glenvale AFC (folded) | 0 | ||
| Irvine Victoria Thistle | 3 | Hillwood FC (folded) | 0 | ||
| Port Glasgow Juniors (folded) | 0 | Glasgow Red Star Athletic | 3 | ||
| Pollok United (folded) | 0 | Hillwood FC Whites | 3 | ||
| Busby AFC | 3 | Busby Amateurs | 0 | ||
| Knightswood FC | 3 | Cambuslang Rangers | 0 | ||
| Castlemilk Boys Club | 3 | North Kelvin United | 0 |